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Availability of furosemide and ethacrynicacid by mid 1960s revolutionized the pattern of diureticuse. Correlations have beenobserved between p53 expression and VEGF expression and micro-vessel densityin different tumour types [ 23 , 15]. Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, McClanahan T, Murphy E, YuanW, Wagner SN, Barrera JL, Mohar A, Verastegui E, Zlotnik A (2001) Involvement of chemo-kine receptors in breast cancer metastasis.

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